Picasso's, for my money, is the best of the Buffalo style. Fluffy dough, generous sweet sauce, lots of cheese and cup char pepperoni full of grease, and a proprietary spice dusting that really seals the deal. I worked at the Lancaster location when I was a teenager and it didn't even ruin it for me, so you know it's good pizza. My family has been going there almost every Saturday since 1992.
I will note that Buffalo style, almost universally, gets better in the winter. I think it has to do with the humidity. There's nothing better than a hot cheese pep on a snowy January night.